• Characterization of the degree of food processing in the European Prospective Investigation into Cancer and Nutrition: Application of the Nova classification and validation using selected biomarkers of food processing 

      Huybrechts, Inge; Rauber, Fernanda; Nicolas, Geneviève; Casagrande, Corinne; Kliemann, Nathalie; Wedekind, Roland; Biessy, Carine; Scalbert, Augustin; Touvier, Mathilde; Aleksandrova, Krasimira; Jakszyn, Paula; Skeie, Guri; Bajracharya, Rashmita; Boer, Jolanda M. A.; Borné, Yan; Chajes, Veronique; Dahm, Christina C.; Dansero, Lucia; Guevara, Marcela; Heath, Alicia K.; Ibsen, Daniel B.; Papier, Keren; Katzke, Verena; Kyrø, Cecilie; Masala, Giovanna; Molina-Montes, Esther; Robinson, Oliver J. K.; Santiuste de Pablos, Carmen; Schulze, Matthias B.; Simeon, Vittorio; Sonestedt, Emily; Tjønneland, Anne; Tumino, Rosario; van der Schouw, Yvonne T.; Verschuren, W. M. Monique; Vozar, Beatrice; Winkvist, Anna; Gunter, Marc J.; Monteiro, Carlos A.; Millett, Christopher; Levy, Renata Bertazzi (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-16)
      Background: Epidemiological studies have demonstrated an association between the degree of food processing in our diet and the risk of various chronic diseases. Much of this evidence is based on the international Nova classification system, which classifies food into four groups based on the type of processing: (1) Unprocessed and minimally processed foods, (2) Processed culinary ingredients, ...
    • Cigarette Smoking and Endometrial Cancer Risk: Observational and Mendelian Randomization Analyses 

      Dimou, Niki; Omiyale, Wemimo; Biessy, Carine; Viallon, Vivian; Kaaks, Rudolf; O'Mara, Tracy A.; Aglago, Elom K.; Ardanaz, Eva; Bergmann, Manuela M.; Bondonno, Nicola P.; Braaten, Tonje; Colorado-Yohar, Sandra M.; Crous-Bou, Marta; Dahm, Christina C.; Fortner, Renée T.; Gram, Inger Torhild; Harlid, Sophia; Heath, Alicia K.; Idahl, Annika; Kvaskoff, Marina; Nøst, Therese Haugdahl; Overvad, Kim; Palli, Domenico; Perez-Cornago, Aurora; Sacerdote, Carlotta; Sánchez, Maria-Jose; Schulze, Matthias B.; Severi, Gianluca; Simeon, Vittorio; Tagliabue, Giovanna; Tjønneland, Anne; Truong, Thérése; Tumino, Rosario; Johansson, Mattias; Weiderpass, Elisabete; Murphy, Neil; Gunter, Marc J.; Lacey, Ben; Allen, Naomi E.; Dossus, Laure (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-16)
      Background: Current epidemiologic evidence indicates that smoking is associated with a lower endometrial cancer risk. However, it is unknown if this association is causal or confounded. To further elucidate the role of smoking in endometrial cancer risk, we conducted complementary observational and Mendelian randomization (MR) analyses.<p> <p>Methods: The observational analyses included 286,415 ...
    • Long-term weight change and risk of breast cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) study 

      Ellingjord-Dale, Merete; Christakoudi, Sofia; Weiderpass, Elisabete; Panico, Salvatore; Dossus, Laure; Olsen, Anja; Tjønneland, Anne; Kaaks, Rudolf; Schulze, Matthias B.; Masala, Giovanna; Gram, Inger Torhild; Skeie, Guri; Rosendahl, Ann H.; Sund, Malin; Key, Tim; Ferrari, Pietro; Gunter, Marc; Heath, Alicia K; Tsilidis, Konstantinos K; Riboli, Eilo; Sánchez, Maria-Jose; Lopez, Maria-Dolores Chirlaque; Peppa, Eleni; Trichopoulou, Antonia; Martimianaki, Georgia; Agudo, Antonio; Santiuste, Carmen; Ardanaz, Eva; Amiano, Pilar; Boutron-Ruault, Marie-Chiristine; Simeon, Vittorio; Berrino, Franco; Tumino, Rosario; Severi, Gianluca; Stocks, Tanja; Turzanski-Fortner, Renée; Rylander, Charlotta; Aune, Dagfinn; Dahm, Christina Catherine (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-23)
      Background: The role of obesity and weight change in breast-cancer development is complex and incompletely understood. We investigated long-term weight change and breast-cancer risk by body mass index (BMI) at age 20 years, menopausal status, hormone replacement therapy (HRT) and hormone-receptor status.<p><p> Methods: Using data on weight collected at three different time points from women ...
    • Plasma concentrations of advanced glycation end-products and colorectal cancer risk in the EPIC study 

      Aglago, Elom K.; Schalkwijk, Casper G.; Freisling, Heinz; Fedirko, Veronika; Hughes, David J.; Jiao, Li; Dahm, Christina C.; Olsen, Anja; Tjønneland, Anne; Katzke, Verena; Johnson, Theron; Schulze, Matthias B.; Aleksandrova, Krasimira; Masala, Giovanna; Sieri, Sabina; Simeon, Vittorio; Tumino, Rosario; Macciotta, Alessandra; Bueno-De-Mesquita, Bas; Skeie, Guri; Gram, Inger Torhild; Sandanger, Torkjel M; Jakszyn, Paula; Sánchez, Maria-Jose; Amiano, Pilar; Colorado-Yohar, Sandra; Barricarte, Aurelio; Perez-Cornago, Aurora; Mayén, Ana-Lucia; Weiderpass, Elisabete; Gunter, Marc J.; Heath, Alicia K.; Jenab, Mazda (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-29)
      Advanced glycation end-products (AGEs) are a heterogeneous group of compounds formed by the non-enzymatic reaction between amino acids and reducing sugars, or dicarbonyls as intermediate compounds. Experimental studies suggest that AGEs may promote colorectal cancer, but prospective epidemiologic studies are inconclusive. We conducted a case–control study nested within a large European cohort. Plasma ...
    • Prediagnostic Blood Selenium Status and Mortality among Patients with Colorectal Cancer in Western European Populations 

      Baker, Jacqueline Roshelli; Umesh, Sushma; Jenab, Mazda; Schomburg, Lutz; Tjønneland, Anne; Olsen, Anja; Marie-Christine, Boutron-Ruault; Rothwell, Joseph A.; Severi, Gianluca; Katzke, Verena; Johnson, Theron; Schulze, Matthias B.; Masala, Giovanna; Agnoli, Claudia; Simeon, Vittorio; Tumino, Rosario; Bueno-De-Mesquita, Bas; Gram, Inger Torhild; Skeie, Guri; Bonet, Catalina; RodrÍguez-Barranco, Miguel; Houerta, José María; Gylling, Björn; Van Guelpen, Bethany; Perez-Cornago, Aurora; Aglago, Elom; Freisling, Heinz; Weiderpass, Elisabete; Cross, Amanda J.; Heath, Alicia K.; Hughes, , David J.; Fedirko, Veronika (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-22)
      A higher selenium (Se) status has been shown to be associated with lower risk for colorectal cancer (CRC), but the importance of Se in survival after CRC diagnosis is not well studied. The associations of prediagnostic circulating Se status (as indicated by serum Se and selenoprotein P (SELENOP) measurements) with overall and CRC-specific mortality were estimated using multivariable Cox proportional ...